Download Model 665 Intermediate Ventilator User`s Manual

Model ‘665’
Intermediate Ventilator
User’s Manual
Model ‘665’ Intermediate Ventilator
Model ‘665A’ Intermediate Ventilator
MA1 55-0798
MA1 55-0806
Publication 5233-001-REV-A
WEEE/RoHS Compliance Statement
EU Directives WEEE and RoHS
To Our Valued Customers:
We are committed to being a good corporate citizen. As part of that commitment,
we strive to maintain an environmentally conscious manufacturing operation. The
European Union (EU) has enacted two Directives, the first on product recycling
(Waste Electrical and Electronic Equipment, WEEE) and the second limiting the use
of certain substances (Restriction on the use of Hazardous Substances, RoHS).
Over time, these Directives will be implemented in the national laws of each EU
Member State.
Once the final national regulations have been put into place, recycling will be offered
for our products which are within the scope of the WEEE Directive. Products falling
under the scope of the WEEE Directive available for sale after August 13, 2005 will
be identified with a “wheelie bin” symbol.
Two Categories of products covered by the WEEE Directive are currently exempt
from the RoHS Directive – Category 8, medical devices (with the exception of
implanted or infected products) and Category 9, monitoring and control instruments.
Most of our products fall into either Category 8 or 9 and are currently exempt from
the RoHS Directive. We will continue to monitor the application of the RoHS
Directive to its products and will comply with any changes as they apply.
• Do Not Dispose Product with Municipal Waste
• Special Collection/Disposal Required
Table of Contents
Harvard Apparatus Model ‘665’ Small Animal Ventilator
1
SUBJECT
PAGE NO.
General Information - Warranty and Repairs ......2
Specifications ........................................................3
Description ............................................................4
Operation ............................................................5-7
Mounting and Adjustment Instructions ..............8
Parts List ................................................................9
Ventilation Graph..................................................10
Schematic of the 665 Ventilator ........................11
General Information
Harvard Apparatus Model ‘665’ Small Animal Ventilator
2
Serial Numbers
All inquires concerning our product should refer to the serial number of the unit.
Serial numbers are located on the rear of the chassis.
Calibrations
All electrical apparatus is calibrated at rated voltage and frequency. While the flow
will stay calibrated, the peak will vary.
W a rr a n t y
Harvard Apparatus warranties this instrument for a period of two years from date of
purchase.At its option, Harvard Apparatus will repair or replace the unit if it is found
to be defective as to workmanship or material.
This warranty does not extend to damage resulting from misuse, neglect or abuse,
normal wear and tear, or accident.
This warranty extends only to the original customer purchaser.
IN NO EVENT SHALL HARVARD APPARATUS BE LIABLE FOR INCIDENTAL OR
CONSEQUENTIAL DAMAGES. Some states do not allow exclusion or limitation of
incidental or consequential damages so the above limitation or exclusion may not
apply to you. THERE ARE NO IMPLIED WARRANTIES OF MERCHANTABILITY,
OR FITNESS FOR A PARTICULAR USE, OR OF ANY OTHER NATURE. Some states
do not allow this limitation on an implied warranty, so the above limitation may not
apply to you.
If a defect arises within the two-years warranty period, promptly contact Harvard
Apparatus, Inc. 84 October Hill Road, Building 7, Holliston, Massachusetts
01746-1371 using our toll free number 1-800-272-2775. Goods will not be accepted
for return unless an RMA (returned materials authorization) number has been issued
by our customer service department. The customer is responsible for shipping
charges. Please allow a reasonable period of time for completion of repairs, replacement and return. If the unit is replaced, the replacement unit is covered only for the
remainder of the original warranty period dating from the purchase of the original
device.
This warranty gives you specific rights, and you may also have other rights which vary
from state to state.
R e p a i r F a c i l i t i e s a n d P a rt s
Harvard Apparatus stocks replacement and repair parts. When ordering, please
describe parts as completely as possible, preferably using our part numbers. If practical, enclose a sample or drawing.We offer a complete reconditioning service.
CAUTION
This pump is not registered with the FDA and is not for clinical use on human
patients.
CAUTION: Not for clinical use on human patients.
Specifications
Harvard Apparatus Model ‘665’ Small Animal Ventilator
3
Model ‘665’ Ventilator Specifications
Volume
Adjustable from 4 to 100 cc/stroke while Ventilator is
running
Rate
Adjustable from 10 to 100 strokes/min while Ventilator
is running
Phase Control
Percentage of inspiration can be adjusted from 25 to
50% of respiratory cycle while Ventilator is running
Port Size:
ID
OD
8 kg (17 lb)
6.4 mm (1/4 in)
7.9 mm (5/16 in)
Dimensions, H x W x D
35 x 45 x 20 cm (14 x 18 x 8 in)
Weight
18 kg (37 lb)
Catalog No.
Model
Power
55-0798
665
115 VAC, 60 Hz
55-0806
665A
230 VAC, 50 Hz
Accessory
55-2810
Overhaul Kit for Intermediate Animal Ventilator; contains O-rings, valve
springs, lubricants, etc. to overhaul Ventilator
Description & Features
Harvard Apparatus Model ‘665’ Small Animal Ventilator
4
Model 665 is a positive pressure, artificial respiration pump for use with small animals. It consists of a 1/15 H.P. permanent magnet motor operated by a solid state
motor speed control, linkages, cylinder and piston assembly and cam operated
slide valve. All of the mechanics and electronics are contained in a sheet metal
housing.
The linkages are so designed that the piston almost touches the end of the cylinder at each stroke regardless of the stroke volume. This insures that all of the air
taken into the pump is expelled at each stroke. The volume is adjustable while the
pump is running by means of the black knob on the top. The volume is indicated
on the side.
The pump is designed to use one of three different sized pistons; 25cc, 50cc, and
100cc. In all cases the piston travel is the same but the cylinders are different
diameters.
Operation
Harvard Apparatus Model ‘665’ Small Animal Ventilator
5
E l e c t r i c a l G ro u n d i n g
The pump is equipped with a three wire ground cord. The grounding should be kept
intact.
S t ro k e Vo l u m e A d j u s t m e n t
The stroke volume is adjusted by a large black knob at the top of the pump with the
volume being indicated on the etched plate attached to the side of the pump housing. The smaller black knob on the volume pointer must be turned counterclockwise
to unlock the large black knob at the top of the pump. Turn the smaller knob clockwise to lock the Stroke Volume Adjustment after positioning.
Hook-up to Animal
A “Y” Connection should be inserted between the connection to the animal (cannula, etc.), and the two tubes coming from the pump. Dead space is minimized if the
“Y” is as close to the animal as possible.
Exhaust
to Atmosphere
Expired Air
“Y” Connector
(As close to animal
as possible)
To
Animal
Output
Optional
Recycling
Room Air
(or non-explosive
gas mixture)
Inspired Air
M o t o r C o n t ro l R a t e
Rate – This control sets the number of complete strokes per minute of the
piston pump.
Operation (Cont’d)
Phase Adjustment
Phase – This control sets the percentage duration of inspiration. If this control
is set at 50, then the duration of inspiration and the duration of expiration are
equal. It is recommended that the user verify the actual rate when using the
phase control at maximum. The following page illustrates this effect.
Volume – Refer to the ventilation graph on page 4 to select the appropriate
tidal volume as a function of body weight
Phase Ratio (% inspiration)
50
50/50
45/55
40/60
35/65
30/70
25/75
40
Actual rate in strokes per min
Harvard Apparatus Model ‘665’ Small Animal Ventilator
6
30
20
10
0
0
10
20
30
Rate on strokes per min dial
40
50
Operation (Cont’d)
Harvard Apparatus Model ‘665’ Small Animal Ventilator
7
T y p i c a l P l o t o f A c t u a l S t ro k e R a t e a t Va r i o u s P h a s e R a t i o s
a n d S t ro k e s
Note: Actual I/E ratio range is 25/75 to 50/50.
The graph to left, taken from tests on a Harvard Model 613 Ventilator, is typical of the
performance from a dual phase motor control pump. As observed, actual stroke rate
varies considerably as the phase ratio reaches its outer limits. Users should be aware
of this relationship and develop appropriate curves to assure accurate experimental
data.
Maintenance
Pump Mechanism
The entire pump mechanism is available for inspection by removing the back panel
(opposite side from volume calibration). All bearings and points of sliding contact
should be lubricated every 3-6 months with a light machine oil (Part No. 0606-060,
Oil - One oz. Btl). A finger full of the silicone lubricant provided should be smeared
inside the cylinder. At the same time the slide valve block should be removed by
removing the two outside screws and its center valve lubricated with the silicone
grease. Do not misplace the “O” rings between the cylinder and valve block. Also, be
careful not to cut the “O” rings when replacing valve in block.
Control
The solid state dual phase motor control needs no attention. A safety fuse is provided to protect the motor and control in the event of mechanical overload or accident.
A schematic of the control is included.
Motor
The motor gearbox is equipped with oilers on the output shaft bearings. A few drops
of light machine oil should be added every 3-6 months.
Mounting & Adjustment Instructions
Harvard Apparatus Model ‘665’ Small Animal Ventilator
8
G e n e r a l I n f o rm a t i o n
The Model 665 Ventilator is designed so that 100 cc and 25 cc cylinder and piston
assemblies can be interchanged.
P ro c e d u re
1.
Remove the back panel of the pump (opposite side from volume calibration).
2.
Remove the name plate by removing the three screws.
3.
Remove the slide valve block by means of the two outside screws. Save
the “O” rings.
4.
Remove the side plate by removing the 2 screws. This will expose the fasteners holding the cylinder.
5.
Rotate the motor by hand or electrically, until the hex block on the piston
rod is visibly protruding from the cylinder.
6.
Using a 3/32 Allen wrench, separate the piston assembly from the 3/8
round piston rod and push the piston into the cylinder.
7.
Remove the screws holding the cylinder to the aluminum panel.
8.
The entire piston and cylinder can now be removed.
9.
Put the new piston assembly into the new cylinder and replace. Lubricate
the piston and cylinder with a finger full of the silicone grease provided
with the pump.
10. Adjust the position of the piston so that the piston is within 1/16" of the
bottom of the cylinder at the extreme end of its travel. The motor must be
rotated for this adjustment.
11. Replace the slide valve.
12. Change the volume plate.
Adjustment Notes
The cylinder must be aligned on piston axis to prevent leakages or binding.
In some cases, the valve setting may need a slight readjustment for different cylinders.
When the valve is adjusted correctly, suction and discharge pressures should be nearly equal. This can be tested by placing a finger over the port tubes.
Parts Listing
9
Harvard Apparatus Model ‘665’ Small Animal Ventilator
Valve Block Assembly for 25 and 100 cc Models
5003-007
0670-138
5013-001(4)
5013-012(2)
0670-191
5013-019
0670-103
5124-003
0670-024
0670-064
0670-027
0670-026
5116-006
5140-006
5013-080
Part No.
Description
0670-024
Valve
0670-026
Retainer-Spring (small bore)
0670-027
Spring-Valve Rod
0670-028
Cap-Valve Block
0670-064
Retainer-Spring (large bore)
0670-103
Fitting Tube
0670-191
Spring-Ball
0670-138
Assy-Valve (black solder)
5013-001
‘O’ Ring - Parker #2-12
5013-012
‘O’ Ring - Parker #2-11
5013-019
‘O’ Ring - Parker #2-13
5116-006
Bolt - Hex HD 1/4-28 x 3/4
5124-003
Ball - Nylon 3/8 diam
5140-006
Washer - Lock Spring 1/4
Ventilation Graph
Tidal Volume vs. Weight & Rate
for
Laboratory Mammals in Resting State
(Apparatus dead spade must be added)
100
70
200
300 400
600 800 1
3
2
4
5 6
8 10
15
20
30
500
Tidal Volume (ml Ambient Temperature)
Harvard Apparatus Model ‘665’ Small Animal Ventilator
10
40
500
400
400
300
300
200
200
150
150
100
100
80
80
60
50
60
50
Breaths per Minute: 10
40
40
40
15
30
30
50
20
20
20
15
15
25
60
10
8
10
8
70
80
90
30
6
6
5
5
4
4
100
3
3
2
2
40
1
1
0.8
0.8
0.6
0.5
0.5
0.6
0.4
0.4
70
100
200
300 400
(Grams)
600 800 1
2
Tidal Volume
3
4
5 6
8 10
15
(Kilograms)
20
30
40
BLUE #18
BLACK #18
5112-073
5112-081
5145-952
5113-033
5146-037
DS1
F1-115 V 1 AMP
F1-220 V 1/2 AMP
5146-542
W1
S2
0645-034
M1
S1
PART NO.
5153-003
REF DES
THESE COMPONENTS
ARE IN HEAT SHRINK
GROUND LUG
MAIN CHASIS
MC1
GROUND LUG
FRONT PANEL
GREEN #18
GREEN/YELLOW #18
W1
PLUG AC MALE
BROWN #18
F1
FUSE SLOW BLOW
RATIO
20 K
VR 101
BLUE
NO
NC
S2
RED
CAM SWITCH
GRAY
WHITE #18
BLACK #18
NOTE: VR102, R101, D101 & D102 ARE
ALL PART OF THE 5153-003 SUBASSEMBLY
D101
1N + 148
D102
1N + 148
R101
12K
CCW
CW
S1
POWER SWITCH
BLACK
BLACK
PILOT LIGHT
DS1
BLACK
100K
SPEED
GREEN
VR102
RED
L1
S1
S2
S3
L1
L2
A1
F1
BLUE #18
BLUE #18
A2
MC1
F2
M1
MOTOR
Harvard Apparatus Model ‘665’ Small Animal Ventilator
Schematic of the Ventilator
11