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SAM Technology Confidential February 6, 2004 Using the BioCalibration (Signal Check) to Determine Correct Electrode Placement At the beginning of each SWMT session, after the SWMT program checks the electrode impedances and calibrates the channel gains, the EEG traces are displayed, and the technician is instructed to have the subject blink, look left, look right, then close the eyes. The eye acts like a battery: the cornea is positive relative to the retina. Changes in the distribution of this charge relative to the EEG electrodes will result in large, predictable potential differences across the head. Incorrect electrode placement may produce large eye artifacts in unexpected channels. Such occurrences should alert you to connection errors in the SWMT jack box. This section first demonstrates the predictable eye blink and eye movement signals you should see with a relaxed subject, with electrodes properly placed on the head and plugged into the appropriate jacks in the SWMT jack box. Then some examples of mismappings in the jack box are provided to show the pattern of activity associated with these errors. Finally, a simple electrode tap test is described that will allow you to be certain of proper electrode mapping. This test should be performed for all SWMT electrodes during the first biocal of the day to ensure that all electrodes are placed in the proper positions. It should be repeated during each subsequent SWMT for the subset electrodes that have been unplugged from the SWMT jack box since the prior session. This procedure is explained in more detail in the last section of this document. Correct Electrode Connections Step One - Ask the Patient to Blink During a blink, the eyeballs roll upward, producing a large positive deflection on electrodes above the eye, as noted in Figure 2. The amplitude of the blink artifact decreases rapidly with distance from the eye. Therefore, when you ask the patient to blink, you should see large blink artifacts on FP1 and FP2. There should be similar, but smaller artifacts on the frontal channels (F3, FZ, and F4). The blink artifact on CZ should be even smaller. Blink artifacts will be the smallest and least visible on the parietal channels (P3, P4, POZ). If the blink is small, the blink artifact may not be visible at all on these channels. Because blink amplitude decreases with distance from the eyes, the eye blink artifact on more posterior channels will never be larger than the blink artifact on more anterior channels, unless the electrodes are mismapped in the jack box. So in this step, make sure that the amplitude of the blink artifact decreases regularly from frontal to central to parietal. The magnitude of the blink artifact should be roughly equal on the three frontal channels since they are located roughly the same distance from the eyes. Similarly, the magnitude of the blink artifact on P3 and P4 should be roughly equal to each other (and much smaller than the blink on the frontal channels). Also note that with correct electrode placement, there should be very little activity on the horizontal eye channel, BPF9 when the patient blinks. If the horizontal eye electrodes are placed properly on the face (1 cm lateral and 1 cm below each eye), the blink will produce the same activity on both channels. Since the left eye electrode is referred to the right eye electrode, the blink is canceled and will not appear on the BPF9 trace (remember that the traces that appear on the screen show the difference in electrical potential between the active electrode and the Page 4 of 16