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also be applicable for older versions, but the integrity of the full range of functions cannot be ensured. Among others, PaMiNI uses functions of the Statistic Toolbox, which must be installed. An installation of the SPM Toolbox is not required. There should be no limitations to the operating system except for the restrictions given by MATLAB. However, the use of Microsoft Windows is recommended. For a proper working of PaMiNI an adequate main memory is required, which should be at least 4GB. A capable CPU is also recommended. 3 Installation For installation only copy the “PaMiNI” folder to any directory on your harddisk. It has to be ensured that the folder contains all m-files, the “MNI.nii” file and the “spm_methods” folder with all files in it. No file may be removed from the folder at any time. There is no need to make changes to MATLAB “set path”. 4 Getting started. . . To open PaMiNI first start the MATLAB program and change the “Current Directory” to the PaMiNI directory. Then type “PaMiNI” into the Command Window of MATLAB. Now the graphical user interface of PaMiNI should open, which should look roughly like Figure 1. Figure 1: The PaMiNI graphical user interface immediately after opening 2