Download Analysis of high-speed opto-biological data from excitable tissues

Contents
1 Introduction
1.1 Background and significance . . . . . . . . . . . . . . . . . . . . . . . . . . .
1.2 Objectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
1.3 Thesis outline . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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I Introduction to cardiac electrophysiology and its research
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2 Cardiac electrophysiology
2.1 The heart and the cardiac cycle . . . . . . . . . . . . . . . . . . . . . . . . .
2.2 The cardiac action potential and its propagation . . . . . . . . . . . . . . .
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3 State of the art research
3.1 Computer modelling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
3.2 Mapping of cardiac excitation . . . . . . . . . . . . . . . . . . . . . . . . . .
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II Signal processing and quantification of cardiac mapping
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4 Data conditioning/filtering
4.1 Differential data . . . . . . . . . . . .
4.2 Spatial and Temporal filtering . . . . .
4.3 Baseline wander removal or detrending
4.4 Normalization . . . . . . . . . . . . . .
4.5 Smoothing filters . . . . . . . . . . . .
4.6 Differentiators . . . . . . . . . . . . . .
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5 Cell
5.1
5.2
5.3
5.4
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6 Quantification of arrhythmias
6.1 Time space plots . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
6.2 Phase maps and phase singularities . . . . . . . . . . . . . . . . . . . . . . .
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network analysis
Signal features of interest . . . . . .
Visualizing features . . . . . . . . . .
Quantification of activation patterns
Propagation speed and direction . .
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