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1 Introduction on QTX QTXNetwork (Figure 1.1) is GPU-based computation software for linkage and association analyses of epistasis and environment interaction of complex traits. It contains four functional modules (Figure 1.2): quantitative trait locus (QTL) for linkage analysis, quantitative trait SNP (QTS) for genome-wide association analysis, quantitative trait transcript/protein/metabolite (QTT/P/M) for transcriptome/proteome/metabolome association analysis, and GMDR for data filtering which will be further used in Genome-Wide Association Studies (GWAS). By using the massive parallel nature of multi-GPUs, this mapping tool can perform association analyses on large-scale omics data for complex traits. Fig 1.1: The main window of the QTXNetwork Fig 1.2: The popup window for creating new project for QTL, QTS, QTT/P/M or GMDR 1