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CHAPTER 2. HIGH-THROUGHPUT SEQUENCING
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filtering and what has been chosen in the Side Panel. If you only want to use a subset of the
information, simply select and Copy ( ) the information. The columns in the SNP and DIP tables
have been synchronized to enable merging in a spreadsheet.
Note that if you make a split view of the table and the mapping (see section ??), you will be
able to browse through the SNPs by clicking in the table. This will cause the view to jump to the
position of the SNP.
If you wish to investigate the SNPs further, you can use the filter option (see section ??). Figure
2.107 show how to make a filter that only shows homozygote SNPs.
Figure 2.107: Filtering away the SNPs that have more than one allele variant.
You can also use the filter to show e.g. nonsynonymous SNPs (filter the Amino acid change
column to not being empty as shown in figure 2.108).
Figure 2.108: Filtering the SNP table to only display nonsynonymous SNPs.
2.11.4
Adjacent SNPs affecting the same codon
Figure 2.109 shows an example where two adjacent SNPs are found within the same codon.
The CLC Genomics Workbench can report these SNPs as one SNP in order to evaluate the
combined effect on the translation to protein. If these SNPs were considered individually,