Download SeqScape Software Version 2.1 User Guide

For Users of Earlier Versions of SeqScape Software
For Users of Earlier Versions of SeqScape
Software
Features of v2.0
The following features were introduced in SeqScape Software v2.0:
• Extended Reference Data Group. SeqScape Software v2.0
contains an extended reference data group (RDG). The RDG
contains a known reference sequence and any known nucleotide
or amino acid variants. The RDG available in this new version
of the software enables analysis of simple or complex projects.
The Reference Sequence within the RDG can be a:
– Contiguous reference sequence with a single reading frame.
– Contiguous reference sequence with multiple reading frames.
– Reference sequence constructed from several reference
segments. Each segment can come from different locations in
the genome.
The reference sequence can contain features such as exons,
introns, splice junctions, primer-binding sites, and promoter
regions.
• Heterozygous insertion/deletion mutation. SeqScape
identifies potential instances of this variant which often require
manual review by trained personnel.
• Library searching. You can compare each consensus sequence
to a sequence library to identify the closest match genotype,
allele or haplotype.
• Enhanced reports. You can customize reports. Each variant in
the report is hyperlinked to the sequence data, providing rapid
transition from results to data. The results reports eliminate the
need to manually record results. You can automatically sort and
reorganize any report.
• Password protection and audit trail. The software protects
your data by providing password protection, automatic lockout
when the software is inactive, and three levels of access control.
An audit trail records each manual insertion, deletion, or base
modification, with reasons for each change.
• Integration automation. The software uses an improved
process for setting up samples for automated analysis on
Applied Biosystems 3730/3730xl instruments.
ABI PRISM SeqScape Software v2.1 User Guide
DRAFT
August 28, 2003 2:54 pm, 1_Intro.fm
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