Download Model 665 Intermediate Ventilator User`s Manual
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Model ‘665’ Intermediate Ventilator User’s Manual Model ‘665’ Intermediate Ventilator Model ‘665A’ Intermediate Ventilator MA1 55-0798 MA1 55-0806 Publication 5233-001-REV-A WEEE/RoHS Compliance Statement EU Directives WEEE and RoHS To Our Valued Customers: We are committed to being a good corporate citizen. As part of that commitment, we strive to maintain an environmentally conscious manufacturing operation. The European Union (EU) has enacted two Directives, the first on product recycling (Waste Electrical and Electronic Equipment, WEEE) and the second limiting the use of certain substances (Restriction on the use of Hazardous Substances, RoHS). Over time, these Directives will be implemented in the national laws of each EU Member State. Once the final national regulations have been put into place, recycling will be offered for our products which are within the scope of the WEEE Directive. Products falling under the scope of the WEEE Directive available for sale after August 13, 2005 will be identified with a “wheelie bin” symbol. Two Categories of products covered by the WEEE Directive are currently exempt from the RoHS Directive – Category 8, medical devices (with the exception of implanted or infected products) and Category 9, monitoring and control instruments. Most of our products fall into either Category 8 or 9 and are currently exempt from the RoHS Directive. We will continue to monitor the application of the RoHS Directive to its products and will comply with any changes as they apply. • Do Not Dispose Product with Municipal Waste • Special Collection/Disposal Required Table of Contents Harvard Apparatus Model ‘665’ Small Animal Ventilator 1 SUBJECT PAGE NO. General Information - Warranty and Repairs ......2 Specifications ........................................................3 Description ............................................................4 Operation ............................................................5-7 Mounting and Adjustment Instructions ..............8 Parts List ................................................................9 Ventilation Graph..................................................10 Schematic of the 665 Ventilator ........................11 General Information Harvard Apparatus Model ‘665’ Small Animal Ventilator 2 Serial Numbers All inquires concerning our product should refer to the serial number of the unit. Serial numbers are located on the rear of the chassis. Calibrations All electrical apparatus is calibrated at rated voltage and frequency. While the flow will stay calibrated, the peak will vary. W a rr a n t y Harvard Apparatus warranties this instrument for a period of two years from date of purchase.At its option, Harvard Apparatus will repair or replace the unit if it is found to be defective as to workmanship or material. This warranty does not extend to damage resulting from misuse, neglect or abuse, normal wear and tear, or accident. This warranty extends only to the original customer purchaser. IN NO EVENT SHALL HARVARD APPARATUS BE LIABLE FOR INCIDENTAL OR CONSEQUENTIAL DAMAGES. Some states do not allow exclusion or limitation of incidental or consequential damages so the above limitation or exclusion may not apply to you. THERE ARE NO IMPLIED WARRANTIES OF MERCHANTABILITY, OR FITNESS FOR A PARTICULAR USE, OR OF ANY OTHER NATURE. Some states do not allow this limitation on an implied warranty, so the above limitation may not apply to you. If a defect arises within the two-years warranty period, promptly contact Harvard Apparatus, Inc. 84 October Hill Road, Building 7, Holliston, Massachusetts 01746-1371 using our toll free number 1-800-272-2775. Goods will not be accepted for return unless an RMA (returned materials authorization) number has been issued by our customer service department. The customer is responsible for shipping charges. Please allow a reasonable period of time for completion of repairs, replacement and return. If the unit is replaced, the replacement unit is covered only for the remainder of the original warranty period dating from the purchase of the original device. This warranty gives you specific rights, and you may also have other rights which vary from state to state. R e p a i r F a c i l i t i e s a n d P a rt s Harvard Apparatus stocks replacement and repair parts. When ordering, please describe parts as completely as possible, preferably using our part numbers. If practical, enclose a sample or drawing.We offer a complete reconditioning service. CAUTION This pump is not registered with the FDA and is not for clinical use on human patients. CAUTION: Not for clinical use on human patients. Specifications Harvard Apparatus Model ‘665’ Small Animal Ventilator 3 Model ‘665’ Ventilator Specifications Volume Adjustable from 4 to 100 cc/stroke while Ventilator is running Rate Adjustable from 10 to 100 strokes/min while Ventilator is running Phase Control Percentage of inspiration can be adjusted from 25 to 50% of respiratory cycle while Ventilator is running Port Size: ID OD 8 kg (17 lb) 6.4 mm (1/4 in) 7.9 mm (5/16 in) Dimensions, H x W x D 35 x 45 x 20 cm (14 x 18 x 8 in) Weight 18 kg (37 lb) Catalog No. Model Power 55-0798 665 115 VAC, 60 Hz 55-0806 665A 230 VAC, 50 Hz Accessory 55-2810 Overhaul Kit for Intermediate Animal Ventilator; contains O-rings, valve springs, lubricants, etc. to overhaul Ventilator Description & Features Harvard Apparatus Model ‘665’ Small Animal Ventilator 4 Model 665 is a positive pressure, artificial respiration pump for use with small animals. It consists of a 1/15 H.P. permanent magnet motor operated by a solid state motor speed control, linkages, cylinder and piston assembly and cam operated slide valve. All of the mechanics and electronics are contained in a sheet metal housing. The linkages are so designed that the piston almost touches the end of the cylinder at each stroke regardless of the stroke volume. This insures that all of the air taken into the pump is expelled at each stroke. The volume is adjustable while the pump is running by means of the black knob on the top. The volume is indicated on the side. The pump is designed to use one of three different sized pistons; 25cc, 50cc, and 100cc. In all cases the piston travel is the same but the cylinders are different diameters. Operation Harvard Apparatus Model ‘665’ Small Animal Ventilator 5 E l e c t r i c a l G ro u n d i n g The pump is equipped with a three wire ground cord. The grounding should be kept intact. S t ro k e Vo l u m e A d j u s t m e n t The stroke volume is adjusted by a large black knob at the top of the pump with the volume being indicated on the etched plate attached to the side of the pump housing. The smaller black knob on the volume pointer must be turned counterclockwise to unlock the large black knob at the top of the pump. Turn the smaller knob clockwise to lock the Stroke Volume Adjustment after positioning. Hook-up to Animal A “Y” Connection should be inserted between the connection to the animal (cannula, etc.), and the two tubes coming from the pump. Dead space is minimized if the “Y” is as close to the animal as possible. Exhaust to Atmosphere Expired Air “Y” Connector (As close to animal as possible) To Animal Output Optional Recycling Room Air (or non-explosive gas mixture) Inspired Air M o t o r C o n t ro l R a t e Rate – This control sets the number of complete strokes per minute of the piston pump. Operation (Cont’d) Phase Adjustment Phase – This control sets the percentage duration of inspiration. If this control is set at 50, then the duration of inspiration and the duration of expiration are equal. It is recommended that the user verify the actual rate when using the phase control at maximum. The following page illustrates this effect. Volume – Refer to the ventilation graph on page 4 to select the appropriate tidal volume as a function of body weight Phase Ratio (% inspiration) 50 50/50 45/55 40/60 35/65 30/70 25/75 40 Actual rate in strokes per min Harvard Apparatus Model ‘665’ Small Animal Ventilator 6 30 20 10 0 0 10 20 30 Rate on strokes per min dial 40 50 Operation (Cont’d) Harvard Apparatus Model ‘665’ Small Animal Ventilator 7 T y p i c a l P l o t o f A c t u a l S t ro k e R a t e a t Va r i o u s P h a s e R a t i o s a n d S t ro k e s Note: Actual I/E ratio range is 25/75 to 50/50. The graph to left, taken from tests on a Harvard Model 613 Ventilator, is typical of the performance from a dual phase motor control pump. As observed, actual stroke rate varies considerably as the phase ratio reaches its outer limits. Users should be aware of this relationship and develop appropriate curves to assure accurate experimental data. Maintenance Pump Mechanism The entire pump mechanism is available for inspection by removing the back panel (opposite side from volume calibration). All bearings and points of sliding contact should be lubricated every 3-6 months with a light machine oil (Part No. 0606-060, Oil - One oz. Btl). A finger full of the silicone lubricant provided should be smeared inside the cylinder. At the same time the slide valve block should be removed by removing the two outside screws and its center valve lubricated with the silicone grease. Do not misplace the “O” rings between the cylinder and valve block. Also, be careful not to cut the “O” rings when replacing valve in block. Control The solid state dual phase motor control needs no attention. A safety fuse is provided to protect the motor and control in the event of mechanical overload or accident. A schematic of the control is included. Motor The motor gearbox is equipped with oilers on the output shaft bearings. A few drops of light machine oil should be added every 3-6 months. Mounting & Adjustment Instructions Harvard Apparatus Model ‘665’ Small Animal Ventilator 8 G e n e r a l I n f o rm a t i o n The Model 665 Ventilator is designed so that 100 cc and 25 cc cylinder and piston assemblies can be interchanged. P ro c e d u re 1. Remove the back panel of the pump (opposite side from volume calibration). 2. Remove the name plate by removing the three screws. 3. Remove the slide valve block by means of the two outside screws. Save the “O” rings. 4. Remove the side plate by removing the 2 screws. This will expose the fasteners holding the cylinder. 5. Rotate the motor by hand or electrically, until the hex block on the piston rod is visibly protruding from the cylinder. 6. Using a 3/32 Allen wrench, separate the piston assembly from the 3/8 round piston rod and push the piston into the cylinder. 7. Remove the screws holding the cylinder to the aluminum panel. 8. The entire piston and cylinder can now be removed. 9. Put the new piston assembly into the new cylinder and replace. Lubricate the piston and cylinder with a finger full of the silicone grease provided with the pump. 10. Adjust the position of the piston so that the piston is within 1/16" of the bottom of the cylinder at the extreme end of its travel. The motor must be rotated for this adjustment. 11. Replace the slide valve. 12. Change the volume plate. Adjustment Notes The cylinder must be aligned on piston axis to prevent leakages or binding. In some cases, the valve setting may need a slight readjustment for different cylinders. When the valve is adjusted correctly, suction and discharge pressures should be nearly equal. This can be tested by placing a finger over the port tubes. Parts Listing 9 Harvard Apparatus Model ‘665’ Small Animal Ventilator Valve Block Assembly for 25 and 100 cc Models 5003-007 0670-138 5013-001(4) 5013-012(2) 0670-191 5013-019 0670-103 5124-003 0670-024 0670-064 0670-027 0670-026 5116-006 5140-006 5013-080 Part No. Description 0670-024 Valve 0670-026 Retainer-Spring (small bore) 0670-027 Spring-Valve Rod 0670-028 Cap-Valve Block 0670-064 Retainer-Spring (large bore) 0670-103 Fitting Tube 0670-191 Spring-Ball 0670-138 Assy-Valve (black solder) 5013-001 ‘O’ Ring - Parker #2-12 5013-012 ‘O’ Ring - Parker #2-11 5013-019 ‘O’ Ring - Parker #2-13 5116-006 Bolt - Hex HD 1/4-28 x 3/4 5124-003 Ball - Nylon 3/8 diam 5140-006 Washer - Lock Spring 1/4 Ventilation Graph Tidal Volume vs. Weight & Rate for Laboratory Mammals in Resting State (Apparatus dead spade must be added) 100 70 200 300 400 600 800 1 3 2 4 5 6 8 10 15 20 30 500 Tidal Volume (ml Ambient Temperature) Harvard Apparatus Model ‘665’ Small Animal Ventilator 10 40 500 400 400 300 300 200 200 150 150 100 100 80 80 60 50 60 50 Breaths per Minute: 10 40 40 40 15 30 30 50 20 20 20 15 15 25 60 10 8 10 8 70 80 90 30 6 6 5 5 4 4 100 3 3 2 2 40 1 1 0.8 0.8 0.6 0.5 0.5 0.6 0.4 0.4 70 100 200 300 400 (Grams) 600 800 1 2 Tidal Volume 3 4 5 6 8 10 15 (Kilograms) 20 30 40 BLUE #18 BLACK #18 5112-073 5112-081 5145-952 5113-033 5146-037 DS1 F1-115 V 1 AMP F1-220 V 1/2 AMP 5146-542 W1 S2 0645-034 M1 S1 PART NO. 5153-003 REF DES THESE COMPONENTS ARE IN HEAT SHRINK GROUND LUG MAIN CHASIS MC1 GROUND LUG FRONT PANEL GREEN #18 GREEN/YELLOW #18 W1 PLUG AC MALE BROWN #18 F1 FUSE SLOW BLOW RATIO 20 K VR 101 BLUE NO NC S2 RED CAM SWITCH GRAY WHITE #18 BLACK #18 NOTE: VR102, R101, D101 & D102 ARE ALL PART OF THE 5153-003 SUBASSEMBLY D101 1N + 148 D102 1N + 148 R101 12K CCW CW S1 POWER SWITCH BLACK BLACK PILOT LIGHT DS1 BLACK 100K SPEED GREEN VR102 RED L1 S1 S2 S3 L1 L2 A1 F1 BLUE #18 BLUE #18 A2 MC1 F2 M1 MOTOR Harvard Apparatus Model ‘665’ Small Animal Ventilator Schematic of the Ventilator 11