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Mr. SQUID User’s Guide top of a grain boundary in a specially prepared substrate. The substrate was a ‘bi-crystal,” created by fusing together two crystals with different orientations. Such a process cannot be extended to integrated circuits or to large-scale manufacturing, but at present it has resulted in the most sensitive YBCO SQUIDs ever produced and is the junction technology employed in the manufacture of Mr. SQUID® since early 1996. Fused crystal boundary Superconductor region 1 region 2 Substrate Figure 5-12 Schematic of bicrystal grain boundary Josephson junction showing the relationship between the fused substrate and relative orientations of the two regions of the YBCO film. STAR Cryoelectronics, LLC 45