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Table of Contents Introduction to ChipInspector.............................................................................................................. 4 What is Genomatix ChipInspector?................................................................................................... 4 Data Analysis................................................................................................................................... 4 Analysis Background .................................................................................................................... 4 File Requirements ........................................................................................................................ 6 Steps in the Statistical Analysis of Microarrays in ChipInspector..................................................... 6 Technical Requirements ...................................................................................................................... 9 Memory Requirements..................................................................................................................... 9 Operating Systems .......................................................................................................................... 9 Java Runtime Environment ............................................................................................................ 10 Browser......................................................................................................................................... 11 Installation and Configuration of ChipInspector.................................................................................. 12 Download...................................................................................................................................... 12 Get Login and Password ................................................................................................................ 14 Registration ............................................................................................................................... 14 Change Password....................................................................................................................... 16 Password Policy ......................................................................................................................... 17 Installation .................................................................................................................................... 18 Configuration of ChipInspector....................................................................................................... 20 Proxy Configuration.................................................................................................................... 21 SSL Configuration....................................................................................................................... 22 Check for Updates...................................................................................................................... 23 Configuration of Statistical Analysis Behavior .............................................................................. 26 Data Storage Settings ................................................................................................................ 27 The ChipInspector Workspace Area ................................................................................................... 28 Project Management Panel ............................................................................................................ 28 Main Panel .................................................................................................................................... 28 Memory Monitor ............................................................................................................................ 29 Log File Monitor............................................................................................................................. 29 Project Tree...................................................................................................................................... 30 Creating a New Project Tree .......................................................................................................... 30 Opening an Existing Project Tree ................................................................................................... 30 Saving the Project Tree ................................................................................................................. 30 Deleting a Project Tree .................................................................................................................. 30 Projects ............................................................................................................................................ 31 Creating a New Project .................................................................................................................. 31 Importing Data Files into a Project ................................................................................................. 32 Data Import Interface ................................................................................................................ 33 Editing a Project ............................................................................................................................ 37 Deleting a Project .......................................................................................................................... 37 Project Data Files .......................................................................................................................... 37 Editing a Data File...................................................................................................................... 37 Deleting a Data File.................................................................................................................... 38 Analyses ........................................................................................................................................... 38 Creating a New Analysis ................................................................................................................ 38 Editing an Analysis......................................................................................................................... 39 Designing an Analysis .................................................................................................................... 39 Analysis Settings ........................................................................................................................ 42 Starting an Analysis.................................................................................................................... 46 Committing an Analysis for a Batch Job ...................................................................................... 47 Creating and Starting a Batch Job............................................................................................... 47 Redoing an Analysis....................................................................................................................... 49 Statistics Curve ................................................................................................................................. 49 Cluster View...................................................................................................................................... 52 Result List......................................................................................................................................... 53 Exporting Results........................................................................................................................... 54 © 2007 Genomatix Software GmbH 2