Download NOTE - Harvard Apparatus
Transcript
Introduction To The PHD ULTRA™ Introduction To The PHD ULTRA™ Pump PRODUCT OVERVIEW – THEORY OF OPERATION The PHD ULTRA™ Syringe Pump series is a family of high-accuracy, microliter- and milliliter-compatible pumps designed for versatile technical use including mass spectroscopy, calibration, drug and nutritional infusions, microdialysis, dispensing, chromatography and LC/HPLC.The PHD ULTRA™ incorporates a microprocessor controlled, small step angle stepping motor that drives a lead screw and Pusher Block. Advanced micro-stepping techniques are employed to further reduce the step angle to eliminate flow pulsation. The pump is engineered to provide flow accuracy within 0.35% and reproducibility within 0.05%. The PHD ULTRA™ uses a touchscreen interface and advanced software to control operation. External I/O interfaces permit external control via an independent computer or device.The application software provides convenient selection of common syringe models from a Syringe Lookup Table, as well as insertion of custom syringe specifications.The system is then able to calculate the cross-sectional area of the syringe selected and calibrate the flow rate and volume accumulation, displaying real-time operating characteristics via on-screen graphics. PUMP MODELS The PHD ULTRA™ Syringe Pump is available in three models designed for different operating environments and varying degrees of operational flexibility. • Infusion Only: This model supports infusion operations at user-definable flow rates and with selectable target volume or time values to control the total infusion volume. The entry-level Infusion Only model does not include programmable, user-defined methods. • Infusion/Withdrawal: This model supports infusion and withdrawal operations at user-definable flow rates and with selectable target volume or time values to control the total volume pumped for both the infusion and withdrawal portions of a procedure. This model provides access to many of the advanced method programming options of the PHD ULTRA™, but only supports a single stored Method. • Infusion/Withdrawal Programmable: This model supports both infusion and withdrawal operations, and can use both simpified pumping profiles or the more advanced pumping profiles and I/O settings that permit interactions with external devices. In addition to supporting all of the advanced programming tools available on the PHD ULTRA™, this model also allows users to create and store multiple user-defined Methods on the pump. ✐ NOTE: This manual has been written to accommodate Infuse/Withdraw/Programmable configurations. Where features/capabilities are not available in the Infuse Only or Infuse/Withdraw basic models, we have identified that in the manual. PUMP CONFIGURATIONS The PHD ULTRA™ Syringe Pump is available in the following configurations: • Standard Pump: This configuration is the most common. It consists of a single unit with the syringe pumping mechanism attached to the top of the control box. • Remote Pump: This configuration is a two piece unit, with the syringe pumping mechanism and the control box separated by a 30 foot cable. Two meter, one meter and 0.5 m cables are available for purchase separately for RS-485 remotes. A 6 foot cable is available for the Legacy remotes. • Push/Pull Pump: This configuration consists of a single unit with the syringe pumping mechanism attached to the top of the control box. The pump can hold up to four syringes; 2 on either side of the pusher block. The pump can simultaneously infuse and withdraw the exact same amount. • Satellite Pump Units: Satellite units consist of a syringe pumping mechanism and control electronics but do not have a user interface. They are powered and controlled from a master/stand-alone PHD ULTRA™ via the RS-485 cable. Publication 5419-002-Rev-E Harvard Apparatus PHD ULTRA™ Syringe Pump Series User’s Manual 10