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miR-AT! User’s Manual v1.6 Table of Contents 1 WHAT IS MIR-AT! ?...................................................................................................................................... 1 2 SEARCHING.................................................................................................................................................... 2 3 RESULTS......................................................................................................................................................... 4 3.1 Gene and Transcript Identifiers....................................................................................................................4 3.2 Binding Sites Detail.....................................................................................................................................5 3.3 Score Distributions......................................................................................................................................6 3.4 Functional Annotation using DAVID........................................................................................................... 7 3.5 Gene Expression Upload.............................................................................................................................. 7 3.6 Results Download........................................................................................................................................ 9 4 CLUSTERING................................................................................................................................................ 10 4.1 Similarity Metrics...................................................................................................................................... 10 4.2 Viewing Clustering Results with Java TreeView......................................................................................... 13 4.3 Saving Clustering Results with Java TreeView...........................................................................................16 5 TROUBLESHOOTING.................................................................................................................................. 19 6 VERSION HISTORY..................................................................................................................................... 20 7 REFERENCES............................................................................................................................................... 22 8 ACKNOWLEGEMENTS & PERMISSIONS................................................................................................ 23 9 APPENDIX A.................................................................................................................................................26 -i-