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The Unscrambler User Manual Camo Software AS Box-Behnken design Designs for Constrained Situations, General Principles This chapter introduces “tricky” situations in which classical designs based upon the factorial principle do not apply. Here, you will learn about two specific cases: 1. Constraints between the levels of several design variables; 2. A special case: mixture situations. Each of these situations will then be described extensively in the next chapters. Note: To understand the sections that follow, you need basic knowledge about the purposes and principles of experimental design. If you have never worked with experimental design before, we strongly recommend that you read about it in the previous sections (see What Is Experimental Design?) before proceeding with this chapter. Constraints Between the Levels of Several Design Variables A manufacturer of prepared foods wants to investigate the impact of several processing parameters on the sensory properties of cooked, marinated meat. The meat is to be first immersed in a marinade, then steam cooked, and finally deep-fried. The steaming and frying temperatures are fixed; the marinating and cooking times are the process parameters of interest. The process engineer wants to investigate the effect of the three process variables within the following ranges of variation: Ranges of the process variables for the cooked meat design Process variable Low High 6 hours 18 hours Steaming time 5 min 15 min Frying time 5 min 15 min Marinating time A full factorial design would lead to the following “cube” experiments: The cooked meat full factorial design Sample Mar. Time Steam. Time Fry. Time 1 6 5 5 2 18 5 5 3 6 15 5 4 18 15 5 The Unscrambler Methods Principles of Data Collection and Experimental Design 25