Download A Microfluidic Device for Single Cell Isolation

Abstract
There exists a need for inexpensive and efficient methods to isolate single cells,
especially single tumor cells for single cell analysis to improve treatment methods. We
developed a microfluidic device that traps single beads ranging from 38 to 45 um, similar
to mammalian cells. Our results suggest our device could trap single beads in 60 um
microwells, indicating this device could allow isolation of similarly-sized cells. Our device
could be used for pharmacological testing for personalized medicine and other
applications.
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