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Figure 44
Example of the radius for the second closest set of nearest
neighbors, or n=2
Step 6. Reject outliers
The calculation to determine the boundaries for rejection of
the outlier pixels is defined below in the equations and
diagram.
Assumptions for default value of 1.42 The following
assumptions lead to the default value of 1.42 for this
parameter.
• Normal distribution for pixel intensity, where y-axis
corresponds to pixel frequency and x-axis corresponds to
pixel intensity.
• A 99% confidence interval that the pixels of interest are
contained within the boundaries for rejection.
Feature Extraction for CytoGenomics Reference Guide
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