Download User Manual - AgesGalore
Transcript
Chapter 5 Protocols Protocols determine how photon count data are used to establish a dose response (growth curve). Up to now, the following protocols are implemented: 5.1 5.1.1 MASS Growth curve MASS is an extension of the well-known SAR protocol (single aliquot regeneration) to multi-pixel images, assuming that each pixel represents its own independent source of light and dose/age information, respectively. Thus, MASS performs a SAR protocol on each pixel (yielding new images of spatial equivalent dose distribution, goodness of fit etc.) and on groups of pixels that have been binned on the level of the raw signal data, i.e. regions of interest (ROIs, e.g. for single grains)1 . MASS use the photon count rates from multiple (n > 1) regeneration measurements Λreg (Di , z̃j1 ,j2 ) (5.1) where Di are the regeneration doses (with i = 1...n) and j1 and j2 the indices of the first and the last subsequent image (channel) the raw signal was summed over. Some Di can have the same value but not all of them. j1 and j2 have to be the same for all Di . Thus, the simplest way to obtain the entries for the growth curve LX is LX (Di ) = Λreg (Di , z̃j1 ,j2 ) (5.2) 1 This means especially that the summed ROI raw signal data are converted into photon counts and then used to establish a growth curve. This is an important difference between AgesGalore 1 and AgesGalore 2. With the first, MASS computed equivalent doses for each pixel first and THEN binned/averaged them to a ROI equivalent dose. This is a minute but important difference. 20