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4. Annex
4.1.
Descriptors
4.1.1.
Deterministic Compartment model descriptor
The descriptor file for this kind of models consists of a JSON file containing the following fields:

Outputs: List of output variables of the model. Each output variable contains the fields:
o Description: Short description of the variable.
o Name: Name of the variable.
o Units: Units of the variable.

Inputs: List of input variables of the model. Each input variable contains the fields:
o Description: Short description of the variable.
o Name: Name of the variable.
o Units: Units of the variable.
o MinRange: Minimum allowed value of the variable.
o MaxRange: Maximum allowed value of the variable.
o Range: Summary of the range of the variable.
{
"Outputs":
[
{"description":"Whole Body Oxygen uptake","name":"VO2","units":"l/min"},
{"description":"Arterial Partial Pressure of Oxygen","name":"PaO2","units":"mmHg"},
{"description":"Venous Partial Pressure of Oxygen","name":"PvO2","units":"mmHg"},
{"description":"Mitochondrial
Oxygen","name":"PmO2","units":"mmHg"},
Partial
Pressure
of
{"description":"?","name":"Q","units":"?"},
{"description":"?","name":"Vmax/Q","units":"?"},
],
"Inputs":
[
{"range":"0.2093","maxRange":"0.2093","description":"Fractional
Oxygen","name":"FIO2","minRange":"0.2093","units":"mm Hg"},
Inspired
{"range":"1000-5000","maxRange":"5000.0","description":"mitochondiral maximum oxygen
uptake (Vmax)","name":"VO2NEBP","minRange":"300.0","units":"ml/min"},
{"range":"0.9-1.3","maxRange":"1.3","description":"CO2/O2
ratio","name":"RQ","minRange":"0.9","units":"ratio"},
{"range":"250-760","maxRange":"760.0","description":"Atmospheric
pressure","name":"PB","minRange":"250.0","units":"mm Hg"},
exchange
barometric
Synergy-COPD simulation environment. User manual