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CONTENTS 1. Introduction .................................................................................................................................................... 3 2. Algorithms and parameter settings ................................................................................................................ 4 2.1 Threshold algorithm ...................................................................................................................................... 4 2.2 SaTScan Poisson model ................................................................................................................................. 5 2.3 SaTscan Space-time Permutation model ...................................................................................................... 6 2.4 Farrington algorithm ..................................................................................................................................... 7 2.5 OutbreakP statistic ........................................................................................................................................ 8 3. Colour-coding scheme in CASE interface ........................................................................................................ 9 4. Statistical evaluation Module ........................................................................................................................ 10 4.1 Description of wizard .................................................................................................................................. 10 4.2 Output files from case evaluation module .................................................................................................. 13 References ............................................................................................................................................................ 23 2