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SSCP/Heteroduplex Analysis 163 10. Lee, H.-H., Lo, W.-J., and Choo, K.-B. (1992) Mutational analysis by a combined application of the multiple restriction fragment-single strand conformation polymorphism and the direct linear amplification sequencing protocols. Anal. Biochem. 205, 289 – 293. 11. Inazuka, M., Wenz, H. M., Sakabe, M., Tahira, T., and Hayashi, K. (1997) A streamlined mutation detection sysytem: multicolor post-PCR fluorescence labeling and single-strand conformational polymorphism analysis by capillary electrophoresis. Genome Res. 7, 1094–1103.