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Appendix A Specifications A A.1 Voyager-DE Specifications This section includes the following specifications for the Voyager-DE Workstation: • • • Performance Mass Spectrometer Miscellaneous Table A-1 Voyager-DE Performance Specifications for Installation Condition Specification Resolution (FWHM—Full Width at Half Maximum) in Delayed Extraction mode • ≥800 for Insulin, bovine (3.5 pmol/µl) • ≥1,000 for Myoglobin (4 pmol/µl) • ≥2,000 for Angiotensin I (1.3 pmol/µl) [M+H]+ ion analyzed. Signal-to-Noise Ratio Mass Accuracy in Delayed Extraction mode (difference between the mean of six measurements and the theoretical mass of the sample) Sensitivity • ≥200:1 for IgG (0.6 pmol/µl) • ≥100:1 for BSA (4 pmol/µl) • External Calibration—0.05% • Internal Calibration—0.02% Mass accuracy is the difference between the measured and the theoretical mass of the sample. Routine detection of 5 fmol of neurotensin with signal-to-noise ratio ≥20:1. Table A-2 Voyager-DE Mass Spectrometer Specifications Condition Mass range Specification ≥300,000 Da Upper limit set by suitably ionized biomolecule. Flight tube A-2 Applied Biosystems 1.2 m linear
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