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Appendix A
Specifications
A A.1 Voyager-DE Specifications
This section includes the following specifications for the
Voyager-DE Workstation:
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Performance
Mass Spectrometer
Miscellaneous
Table A-1 Voyager-DE Performance Specifications for Installation
Condition
Specification
Resolution (FWHM—Full Width at Half Maximum)
in Delayed Extraction mode
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≥800 for Insulin, bovine (3.5 pmol/µl)
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≥1,000 for Myoglobin (4 pmol/µl)
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≥2,000 for Angiotensin I (1.3 pmol/µl)
[M+H]+ ion analyzed.
Signal-to-Noise Ratio
Mass Accuracy in Delayed Extraction mode
(difference between the mean of six measurements
and the theoretical mass of the sample)
Sensitivity
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≥200:1 for IgG (0.6 pmol/µl)
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≥100:1 for BSA (4 pmol/µl)
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External Calibration—0.05%
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Internal Calibration—0.02%
Mass accuracy is the difference between the
measured and the theoretical mass of the
sample.
Routine detection of 5 fmol of neurotensin with
signal-to-noise ratio ≥20:1.
Table A-2 Voyager-DE Mass Spectrometer Specifications
Condition
Mass range
Specification
≥300,000 Da
Upper limit set by suitably ionized biomolecule.
Flight tube
A-2
Applied Biosystems
1.2 m linear