Download Exercise 1

Workshop on Bacterial Genomics
6
Go back to your initial results page and see how many proteins have been assigned to the
Arp2/3 complex in S. pombe. Are any of the components characterised by Pfam domains?
Fill in the table on page at the end of the exercise.
The next aim is to identify putative Arp2/3 complex components in the genomes of
trypanosomatids. We’re going to start off with the T. brucei genome. You may take a
number of different approaches:
• using keywords to search the available T. brucei annotation (exercise 1.2).
• browsing predicted Pfam domain catalogue (exercise 1.3).
• using GO annotations and the gene ontology browser (exercise 1.4).
• using BLAST to identify sequences with similarity to known Arp2/3 components
(exercise 1.5).
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