Download Ion Max APPI Source User Manual Version C

4
Optimizing the LCQ Deca XP MAX MS Detector with Your Analyte
Setting Up the MS Detector for APCI/APPI/MS Operation
Setting Up the MS
Detector for
APCI/APPI/MS
Operation
On
Standby
To set up the MS detector for APCI/APPI/MS operation on the XP Plus
1. In Tune Plus, click on the On/Standby button to take the MS detector
out of Standby mode and turn it on. The MS detector begins scanning,
and applies the high voltage to the corona needle, and shows a real-time
display in the Spectrum view.
2. Open the APCITune.LCQTune Tune Method, the Tune Method for
high-flow APCI operation:
a. Choose File > Open to display the Open dialog box.
b. Scroll down until you see the folder C:\Xcalibur\methods. Then,
select the file APCITune.LCQTune.
c. Click on OK to open the file. XP Plus downloads the Tune Method
parameters to the MS detector.
3. Verify that XP Plus opened the Tune Method, as follows:
a. Choose Setup > Change API Source Type to specify the
APCI source. Then, in the Change Source Type dialog box, which
appears, select the APCI option button.
b. Click on OK to return to the Tune Plus window.
c. On the Instrument Setup toolbar, click on the API Source button to
open the APCI Source dialog box (Figure 23).
d. Verify that the settings in your dialog box are similar to those shown
in Figure 23.
• To operate in APPI mode only, set the discharge current to zero.
• To operate in APCI/APPI or APCI mode only set the discharge
current to 5 μA.
e. Click on OK to close the dialog box.
4. If you are operating in APPI or APCI/APPI mode, turn the APPI lamp
on. Verify that the lamp is operating by observing the lamp through the
front window of the Ion Max ion source housing.
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APPI Souce User Manual
Thermo Scientific