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Glossary:
N.D. (no data) Data is not in Watson.
needle draw position offset The difference in the
distance of the needle from the bottom of the vial
from its default position.
negative peak A peak characterized by signal levels
that drop below the baseline level of the detector.
neighboring amino acid The amino acids on either
side of the cleaved amino acid.
NL An abbreviated form of the words normalized
level. This shortened form is used to save space in the
header, for example, NL: 1.98e+003 (1.98 x 103).
nominal sample time Protocol definition. The
theoretical relative time a sample was taken from a
subject after a treatment administration.
non-serial subject (sparse sampling; composite
profile) Protocol definition. A group of subjects that
can be sampled only once or a limited number of
times after treatment administration. It is not
possible to study a subject's time vs. concentration
profile. To create a time vs. concentration response
profile for a treatment, a subject group dosed at the
same time are divided into subsets of subjects that are
sampled at different time points. Sample
concentrations at the same time point are averaged
together, and then the averages at the time
increments are combined to form the time vs.
concentration profile.
no peak Not calculable. No data was returned from
the instrument for the sample or the Watson
application is unable to calculate a solution for the
regression. Not Reportable: user definable string User
assigned flag.
no sites Amino acids in a sequence that follow an
amino acid listed are not susceptible to digestion. For
example, trypsin_k digests at Lysine (K), but if the K
follows a Proline (P) in the sequence, it will not be
digested.
Thermo Scientific
no waste injection A technique that injects the exact
amount of sample requested. Of the three injection
modes, the no waste injection mode uses the least
amount of sample, but it is also the least precise. Use
this injection mode to conserve sample.
nominal molecular weight The calculated mass of a
molecule based on the integer mass number of the
most abundant isotope of each element, for example,
C = 12, H = 1, and O = 16.
normal scan types Scan types that are full and SIM.
Normal scan types all have the same scan rate and
provide unit resolution.
normalization A data analysis procedure where all
peaks are reported with heights relative to the highest
peak height or area in the chromatogram, spectrum,
or map.
See also:
fixed Y-axis normalization mode
normalize Y-axis normalization mode
normalize spectra The action of normalizing spectra
to a common base peak intensity instead of using the
raw intensities from the raw file before it generates
correlation results.
Normalizing the spectra corrects for intensity
discrimination in the correlation results that can
occur if spectra with significantly different absolute
peak intensities are used.
normalize Y-axis normalization mode A display
mode, which is available for the Spectrum view, that
sets the vertical scale equal to the height of the largest
peak in a mass spectrum. In the normalize display
mode, the software always displays the largest peak in
the spectrum at full scale.
See also:
fixed Y-axis normalization mode
nucleic acid Biologically occurring poly-nucleotides
showing the nucleotide residues linked in a specific
sequence by phosphodiester bonds, for example,
DNA and RNA.
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